Comparative Evaluation of Nanofibrous Scaffolding for Bone Regeneration in Critical-Size Calvarial Defects
نویسندگان
چکیده
منابع مشابه
Comparative evaluation of nanofibrous scaffolding for bone regeneration in critical-size calvarial defects.
In a previous study we found that nanofibrous poly(l-lactic acid) (PLLA) scaffolds mimicking collagen fibers in size were superior to solid-walled scaffolds in promoting osteoblast differentiation and bone formation in vitro. In this study we used an in vivo model to confirm the biological properties of nanofibrous PLLA scaffolds and to evaluate how effectively they support bone regeneration ag...
متن کاملComparative study of porous hydroxyapatite/chitosan and whitlockite/chitosan scaffolds for bone regeneration in calvarial defects
Hydroxyapatite (HAP; Ca10(PO4)6(OH)2) and whitlockite (WH; Ca18Mg2(HPO4)2(PO4)12) are widely utilized in bone repair because they are the main components of hard tissues such as bones and teeth. In this paper, we synthesized HAP and WH hollow microspheres by using creatine phosphate disodium salt as an organic phosphorus source in aqueous solution through microwave-assisted hydrothermal method....
متن کاملErratum: Bone regeneration of mouse critical-sized calvarial defects with human mesenchymal stem cells in scaffold
Combination of tissue engineering and cell therapy represents a promising approach for bone regeneration. Human mesenchymal stem cells (hMSCs) have properties that include low immunogenicity, high proliferation rate, and multi-differentiation potential; therefore, they are an attractive seeding source for tissue engineering therapy. Here we found that hMSCs with a scaffold did not affect cell v...
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Craniofacial injuries can result from trauma, tumor ablation, or infection and may require multiple surgical revisions. To address the challenges associated with treating craniofacial bone defects, an ideal material should have the ability to fit complex defects (i.e. be conformable), provide temporary protection to the brain until the bone heals, and enhance tissue regeneration with the delive...
متن کاملAdipose-Derived Purified PSCs Heal Critical-Size Mouse Calvarial Defects
Askarinam, A; Zara, JN; James, AW; Yuan, W; Chiang, M; Nguyen, A; Stoker, D; Pang, S; Corselli, M;Zhang, X; Peault, B; Ting, K; +Soo, C Dental and Craniofacial Research Institute and the Section of Orthodontics, School of Dentistry, UCLA, + 2 UCLA and Orthopaedic Hospital Department of Orthopaedic Surgery, and the Orthopaedic Hospital Research Center, University of California, Los Angeles, Los ...
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ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2009
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2008.0433